- June 10
- New York passes first effective law regulating practice of medicine. [1]
- June 23
- Battle of Landshut, Silesia. [1]
- October 25
- George III ascends the British throne. [1] [309.71]
- December 25
- Jupter Hammon, New York slave, publishes poetry in "An Evening Thought". [1]
1761
- January 7
- Battle at Panipat, India; Afghan army beats Mahratten. [1]
- March 29
- William Pitt sails from England with Marines to attempt to take Belle Isle-en-mer off France. [857.33]
- May 22
- First life insurance policy in US, issued in Philadelphia. [1]
- June 7
- French surrender Belle Isle-en-mer island off France to the English. [857.34]
- June 25
- In Halifax, over 75 years of war between Mi'kmaq and England ends. [1307.12]
- (month unknown)
- English clockmaker John Harrison invents chronometer capable of allowing accurate longitude to be measured on a ship. [1128.28]
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- November 15
- French merchant ship L'Auguste de Bordeaux sinks near Nova Scotia during a storm. [419.64]
- December 16
- Russian army occupies Kolberg. [1]
1762
- January 4
- England declares war on Spain and Naples. [1]
- January 15
- Fraunces Tavern opens in New York City, New York. [1]
- February 2
- Thomas Arnes opera "Artaxerxes" premieres in London. [1]
- February 12
- English fleet occupies Martinique. [1]
- March 17
- First Saint Patrick's Day parade in New York City. [1]
- April 2
- In Bangladesh, a very destructive earthquake occurs. Sixty square miles are said to have been permanently submerged. [53]
- April 5
- British take Grenada, West Indies, from French. [1]
- April 24
- Russia and Prussia signs peace treaty. [1]
- May 5
- Russia and Prussia sign peace treaty. [1]
- May 22
- Sweden and Prussia sign peace treaty. [1]
- Pope Clement XIII officially opens the Trevi Fountain in Rome. [1674.27]
- June 28
- Accession to the throne of Catherine the Great in Russia. [452.48]
- August 22
- First female (Ann Franklin) US newspaper editor, Newport Rhode Island, Mercury. [1]
- October 5
- The opera "Orfeo Ed Euridice" is produced (Vienna). [1]
- November 3
- Spain acquires Louisiana. [1]
- December 9
- British parliament accepts the Treaty of Paris. [1]
- December 21
- James Cook marries Elizabeth Batts. [1]
1763
- February 10
- The Treaty of Paris is signed by Britain, France, and Spain, ending the French-Indian War. France cedes all North American possessions to Britain except Saint Pierre and Miquelon. All French and Spanish territory east of Mississippi is ceded to Britain. [1] [614.138]
- February 12
- John Casteret appointed British minister of foreign affairs. [1]
- February 15
- Austria, Prussia and Saxony sign Peace of Hubertusburg. [1]
- April 19
- English Parliament bans American colonies from printing their own paper money. [393.60]
- April 30
- London Journalist John Wilkes confined in the Tower. [1]
- November 15
- Charles Mason and Jeremiah Dixon begin surveying Mason-Dixon Line between Pennsylvania and Maryland. [1]
- December 2
- Touro shul of Newport, Rhode Island dedicated (oldest existing US synagogue). [1]
1764
- January 24
- Governor Winthrop Telescope, is destroyed in a Harvard fire. [1]
- February 15
- Saint Louis founded as a French trading post by Pierre Laclade Ligue. [1]
- February 21
- John Wilkes thrown out of English House of Commons for "Essay on Women". [1]
- April 3
- Austrian arch duke Jozef crowned himself Roman Catholic king. [1]
- May 5
- Smolny-institution forms in Saint Petersburg for noble girls. [1]
- September 1
- British Parliament passes the Currency Act, effectively assuming control of colonial currency. [545.36]
- September 7
- Stanislaw August Poniatowski is elected king and Grand Duke of Commonwealth of Poland-Lithuania. [1383.8]
- October 25
- John Adams marries Abigail Smith (marriage lasts 54 years). [1]
1765
- January 11
- Frisia bans Voltaires "Traité sur la tolérance". [1]
- January 16
- Charles Messier catalogs M41 (galactic cluster in Canis Major). [1]
- January 23
- Commodore John Byron takes formal possession of the Falkland Islands for England. [1199.37]
- March 22
- The British government passes the Stamp Act, imposing a direct tax on all materials printed for commercial and legal use in the American colonies. [1] [129]
- March 24
- Britain enacts Quartering Act, required colonists to provide temporary housing to British soldiers. [1]
- May 3
- First US medical college opens in Philadelphia; founded by John Morgan, the School of Medicine belonged to the College of Philadelphia (now the University of Pennsylvania). [1]
- May 7
- Admiral Nelson's sailboat HMS Victory runs aground. [1]
- May 29
- Patrick Henry historic speech against the Stamp Act, answering a cry of "Treason!" with, "If this be treason, make the most of it!". [1]
- August 14
- Mass colonists challenge British rule by an Elm (Liberty Tree). [1]
- October 7
- The Stamp Act Congress convenes in New York. [1]
- October 19
- Stamp Act Congress met in New York, wrote decl of rights and liberties. [1]
- November 1
- Stamp Act goes into effect in the British colonies. [1]
- November 23
- People of Frederick County Maryland refuse to pay England's Stamp tax. [1]
1766
- February 11
- Stamp Act declared unconstitutional in Virginia. [1]
- February 14
- Dutch governor Falck signs Treaty of Batticaloa with rebels. [1]
- March 5
- Don Antonio de Ulloa takes possession of Louisiana Terr from French. [1]
- March 8
- Willem V (18) becomes Governor of United Provinces. [1]
- March 17
- Britain repeals Stamp Act. [1]
- March 18
- British Parliament reinstitutes the Stamp Act. [1]
- April 8
- First fire escape patented, wicker basket on a pulley and chain. [1]
- May 9
- John Byron back in England after trip around the world. [1]
- July
- A 2kg stony meteorite falls near Albaneto in the Romagna area of Italy. [523.20]
- November 25
- Pope Clement XIII warns On the dangers of anti-Christian writings. [1]
- December 5
- London auctioneers Christie's hold their first sale. [1]
1767
- May 13
- Mozart's opera "Apollo et Hyacinthus" premieres in Salzburg. [1]
- May 14
- British government disbands Americans import duty on tea. [1]
- June 29
- British passes Townshend Revenue Act levying taxes on America. [1]
- October 18
- Boundary between Maryland and Pennsylvania, the Mason Dixon line, agreed upon. [1]
- December 16
- Van Ritter von Glucks opera "Alceste" premieres. [1]
1768
- February 11
- Samuel Adams letter, circulates around American colonies, opposing Townshend Act taxes. [1]
- February 15
- First mustard manufactured in America advertised, Philadelphia. [1]
- February 20
- First American chartered fire insurance company receives charter (Pennsylvania). [1]
- April 5
- First US Chamber of Commerce forms (New York City, New York). [1]
- June 21
- First US bachelor of medicine degree (Dr John Archer). [1]
- July 7
- Firm of Johann Buddenbrook founded, in Thomas Mann's novel. [1]
- December 6
- First edition of "Encyclopedia Brittanica" published (Scotland). [1]
1769
- April 22
- Madame du Barry becomes King Louis XV's "official" mistress. [1]
- May 7
- Ras Mikael Sehul deposes Ethiopian emperor Iyoas. [1674.27]
- June 7
- Daniel Boone begins exploring the Bluegrass State of Kentucky. [1]
- July 16
- Father Serra founds Mission San Diego, first mission in California. [1] [419.58]
- September 18
- Boston Gazette reports first US piano (a spinet). [1]
- December 12
- Pope Clement XIV proclaims a universal jubilee. [1]
- December 13
- Dartmouth College in New Hampshire received its charter. [1]
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