1400
- December 22
- Birth of Luca della Robbia Italy, sculptor (Madonna of Rose Garden). [1]
1403
- January 11
- Birth of Jan IV Duke of Brabant/Limburg. [1]
- February 22
- Birth of Charles VII king of France (1422-61), drove out English. [1]
1404
- February 9
- Birth of Constantine XI Dragases last Byzantine Emperor. [1]
- February 18
- Birth of Leon B Alberti Italian humanist/architect (Della Pittura). [1]
1405
- March 6
- Birth of Johan II King of Castille. [1]
1406
- January 13
- Birth of Matteo Palmieri Italian writer (Della vita civile). [1]
1409
- March 2
- Birth of John II French duke of Alençon/co-fighter of Jeanne d'arc. [1]
1410
- April 27
- Birth of John Van Lannoy Flemish Governor of Holland/Zealand/West Frisia. [1]
1412
- January 6
- Birth of Joan of Arc Domremy, martyr. [1]
1415
- September 21
- Birth of Frederick III Innsbruck Austria, German Emperor (1440-1493). [1]
1416
- March 27
- Birth of Antonio Squarcialupi composer. [1]
1417
- February 21
- Birth of Louis IX Duke of Bayern (University of Ingolstadt). [1]
- February 23
- Birth of Paul II [Pietro Barbo], Italy, Pope (1464-71). [1]
- March 21
- Birth of St. Nicholas of Flüe in Flüeli, Switzerland; judge, hermit. [37]
1421
- December 6
- Birth of Henry VI king of England (1422-61, 1470-71). [1]
1422
- August 13
- Birth of William Caxton first English printer (Histories of Troy). [1]
1423
- July 3
- Birth of Louis XI king of France (1461-83). [1]
1428
- December 22
- Birth of Richard Neville Warwick second earl of Salisbury. [1]
1431
- January 1
- Birth of Alexander VI [Rodrigo Borgia] Spanish/Italian pope (1492-1503). [1]
1432
- January 15
- Birth of Afonso V "the African" king of Portugal (1438-1481). [1]
- March 30
- Birth of Mehmed II [Fâtih] Sultan of Turkey (1451-81). [1]
- August 15
- Birth of Luigi Pulci Italy, poet (Morgante). [1]
1435
- October 20
- Birth of Andrea Della Robbia Florence, sculptor, nephew of Luca. [1]
1436
- June 6
- Birth of Regiomontanus (Johann Müller) in Königsberg; responsible for modern rediscovery of trigonometry from Greek manuscripts on Ptolemy. [1] [37]
1438
- February 12
- Birth of Adolf van Egmond duke of Gelre/earl of Zutphen. [1]
- April 3
- Birth of John III van Egmont [Manke John], viceroy of Holland. [1]
1440
- January 22
- Birth of Ivan III the Great, Russian czar (1462-1505)/conquered Lithuania. [1]
- February 13
- Birth of Hartmann Schedel German physician/humanist/historian. [1]
- February 22
- Birth of Ladislaus V Posthumus King of Hungary/Bohemia. [1]
1441
- February 9
- Birth of Ali Sjir Neva'i [Fani] Turkish poet/author (Mahbub al-kulub). [1]
- March 24
- Birth of Ernst I elector of Saxon (1464-86). [1]
1442
- April 20
- Birth of Edward IV King (England, 1461-83). [1]
- April 28
- Birth of Edward IV king of England (1461-70, 1471-83). [1]
1443
- December 4
- Birth of Pope Julius II (1503-13), patron of Michelangelo, Bramante, Raphael. [1]
1444
- February 17
- Birth of Rudolf Agricola [Roelof Huysman], Dutch humanist/organist. [1]
- May 17
- Birth of Sandro Botticelli Italian painter (Birth of Venus). [1]
1446
- May 3
- Birth of Margaretha English princess/duchess of Bourgondie. [1]
1449
- January 1
- Birth of Lorenzo de' Medici [The Magnificent] of Florence. [1]
- January 11
- Birth of Domenico Ghirlandajo Italy, renaissance painter. [1]
1451
- January 14
- Birth of Franchinus Gaffurius composer. [1]
- April 22
- Birth of Isabella I of Castile, Queen of Spain (1479-1504), patron of Columbus. [1]
- May 17
- Birth of Engelbert II earl of Nassau-Dillenburg-Dietz/viceroy of Luxembourg. [1]
1452
- March 10
- Birth of Ferdinand II the Catholic, King of Aragon/Sicily (expelled Jews). [1]
- April 15
- Birth of Leonardo da Vinci in Italy; painter/sculptor/scientist/visionary (dies 1519). [1] [5]
- September 21
- Birth of Girolamo Savonarola Florentine monk/preacher/reformer. [1]
- December 22
- Birth of Jakob Obrecht Brabant, composer. [1]
1454
- March 9
- Birth of Amerigo Vespucci; explorer. [1]
1455
- February 22
- Birth of Johannes Reuchlin in Pforzheim, Germany; scholar of ancient Greek and Latin. [37]
- May 3
- Birth of Joâo II the perfect, King of Portugal (1481-95)/took in Spanish Jews. [1]
1456
- March 1
- Birth of Wladyslaw Jagiello king of Bohemia/Hungary (1471/90-1516). [1]
1457
- January 28
- Birth of Henry VII Pembroke Castle, first Tudor king of England (1485-1509). [1]
1459
- February 1
- Birth of Conradus Celtis in Wipfeld, Germany; poet. [37]
- March 2
- Birth of Adrian VI [Adriaan F Boeyens], Netherlands, Pope (1522-23). [1]
- March 6
- Birth of Jacob Fugger German banker/merchant. [1]
- March 22
- Birth of Maximilian I of Habsburg, in Wiener Neustadt; German Emperor/archduke of Austria. [1] [37]
- October 6
- Birth of Martin Behaim in Nürnberg, Germany; produced oldest known globe in existence in 1492. [37]
- December 22
- Birth of Djem Sultan son of Turks sultan Mehmed II. [1]
1460
- April 8
- Birth of Ponce de León San Tervas de Campos Spain, Spanish conqueror/explorer, searched for fountain of youth, found Florida. [1]
1461
- February 6
- Birth of Dzore Drzic Croatian poet. [1]
1462
- February 14
- Birth of Edzard I Cirksena the Great, earl of East-Friesia (1494-1528). [1]
- June 27
- Birth of Louis XII (the Just) king of France (1498-1515). [1]
1463
- January 17
- Birth of Friedrich III (the Wise), Elector of Saxony in Torgau, Germany; protector of Martin Luther, patron of Albrecht Dürer, and Luchas Cranach the Elder, founded the University of Wittenberg in 1502. [1] [37]
- February 24
- Birth of Giovanni Pico della Mirandola Italy, scholar/platonist. [1]
1464
- April 23
- Birth of Johanna van Valois Queen of France. [1]
- Birth of Robert Fayrfax composer. [1]
1465
- February 4
- Birth of French van Brederode leader of Hoeksen. [1]
- February 11
- Birth of Elizabeth of York London, Consort of King Henry VII. [1]
1466
- March 21
- Birth of French van Brederode leader Hoeksen. [1]
- October 26
- Birth of Desiderius Erasmus Holland, scholar/author (In Praise of Folly). [1]
- November 30
- Birth of Andrea Doria Genoese statesman/admiral. [1]
1467
- January 1
- Birth of Sigismund I the old, king of Poland. [1]
- January 14
- Birth of Henry van Stolberg and Wernigerode German Governor/Viceroy of Frisia. [1]
1468
- February 29
- Birth of Paul III last Renaissance pope (1534-49). [1]
- March 28
- Birth of Charles I Duke of Savoy. [1]
1469
- April 15
- Birth of Nanak first guru of Sikhs. [1]
- May 3
- Birth of Niccolo Machiavelli in Florence, Italy; philosopher and writer (The Prince). [1] [129]
- May 19
- Birth of Giovanni della Robbia Italian sculptor. [1]
- May 31
- Birth of Manuel I king of Portugal (1495-1521) during era of exploration. [1]
1470
- May 20
- Birth of Pietro Bembo cardinal/theologian. [1]
- June 30
- Birth of Charles VIII king of France (1483-98), invaded Italy. [1]
- November 2
- Birth of King Edward V of England (1483); deposed, murdered? by Richard III. [1]
1471
- May 21
- Birth of Albrecht Dürer in Nürnberg (Germany); court painter to the Holy Roman Emperors, Maximilian I and Charles V: The Four Horsemen of the Apocalypse, The Passion of Christ, Adam and Eve. [1] [37]
1472
- March 28
- Birth of Fra Bartolomeo monk, Florentine Renaissance painter. [1]
- May 31
- Birth of Erardus van der Mark prince-bishop of Luik/cardinal. [1]
- October 4
- The painter, Lucas Cranach, is born in Bamberg, Germany. [37]
1473
- February 19
- Birth of Nicolaus Copernicus in Torún, Poland (dies 1543); astronomer (heliocentrism). [1] [5]
- March 17
- Birth of James IV king of Scotland (1488-1513). [1]
1474
- February 12
- Birth of Lorenzo Campeggi(o) archbishop of Bologna/diplomat. [1]
- March 21
- Birth of Angela Merici Italian monastery founder/saint. [1]
- September 8
- Birth of Ludovico Ariosto Italy, poet (Orlando Furioso). [1]
1475
- March 6
- Birth of Michelangelo Buonarroti; painter/sculptor/architect (David, Pièta) (dies 1564). [1] [5]
- December 11
- Birth of Leo X [Giovanni de' Medici] Italy, Pope (1513-21). [1]
1477
- January 25
- Birth of Anna de Bretagne wife of Maximilian of Austria and Louis XII. [1]
- July 4
- Birth of the historian, Aventinus (Johannes Turmair) in Abensberg, Germany; publishes a Latin grammar and a history of the Bavarian nobility. [37]
1478
- February 7
- Birth of Sir Thomas More lawyer/lord chancellor of England/saint (Utopia). [1]
- May 26
- Birth of Clement VII [Giulio de' Medici], Italy, Pope (1523-34). [1]
- July 22
- Birth of Philip I (the Handsome) first Habsburg king of Spain (1506). [1]
1479
- March 12
- Birth of Giuliano de' Medici monarch of Florence. [1]
- March 26
- Birth of Vasili III great prince of Moscow (1505-33)/son of Ivan III. [1]
1480
- February 13
- Birth of Hieronymus Aleander [Girólamo Aleandro], Italian diplomat/cardinal. [1]
- April 18
- Birth of Lucretia Borgia murderess (poison)/daughter (Pope Alexander VI). [1]
1481
- March 2
- Birth of Franz von Sickingen in Ebernburg; German defender of the Protestant cause. [1] [37]
1483
- January 12
- Birth of Hendrik van Nassau-Dillenburg en Dietz Governor/Viceroy of Holland. [1]
- February 14
- Birth of Zahir al-Din Mohammed Babur Shah prince/founder Mogols-dynasty. [1]
- February 15
- Birth of Babur founder of Mughal dynasty in India (1526-30. [1]
- March 6
- Birth of Francesco Guicciardini Italy, attorney/president of Romagna. [1]
- March 18
- Birth of Raphael painter (Sistine Madonna). [1]
- March 28
- Birth of Raphael Urbino Italy, painter (School of Athens). [1]
- April 6
- Birth of Raphael [Raffaello Sanzio] Urbino Italy, painter/master builder (Madonna Sistina). [1]
- November 10
- Birth of Martin Luther in Eisleben, Germany; founded Protestantism. [1] [37]
- December 3
- Birth of Nicolaus von Amsdorf; German reformation theologist. [1] [37]
1484
- January 1
- Ulrich Zwingli is born in Wildhaus, Switzerland; influential church reformer in the development of Swiss Protestantism. [37] (1481 [1])
- January 17
- Birth of Georg Spalatin (pseudonym of Georg Burkhardt) in Spalt, Germany (died 1545); close friend and collaborator of Martin Luther. [37]
- February 21
- Birth of Joachim I Nestor elector (Brandenburg, Constitution). [1]
- March 29
- Birth of Johann Spangenberg composer. [1]
- April 23
- Birth of Julius Cæsar Scaliger Italy, scholar (On the Subtlety of Things). [1]
- December 28
- Birth of Joachim Vadianus [von Watt] Swiss physician/mayor of Sankt Gallen. [1]
1485
- April 3
- Birth of Lieven van der Maude [Ammonius] South Netherlands poet. [1]
- December 16
- Birth of Catherine of Aragon Spanish princess/first wife of Henry VIII. [1]
1486
- January 6
- Birth of Martin Agricola (pseudonym of Martin Sore) in Schwiebus; German music scholar and composer in Magdeburg. [1] [37]
- July 14
- Birth of Andrea del Sarto Italy, painter (Recollets). [1]
- November 13
- Birth of Johann Eck (birth name Johann Maier) in Egg, Germany; Catholic priest, Doctor of Theology, professor of theology. [37]
1487
- February 8
- Birth of Ulrich in Reichenweier, Germany; Herzog of Württemberg. [37]
- February 14
- Birth of Henry II of Bavaria bishop of Utrecht/Worms/Freising. [1]
- July 17
- Birth of Esma'il I shah who converted Iran from Sunni to Shi'ah. [1]
- September 10
- Birth of Julius III Counter-Reformation pope (1550-55). [1]
1488
- January 6
- Birth of Helius Eobanus Hessus German poet (Silvae). [1]
- April 21
- Birth of Ulrich von Hutten near Fulda; German poet/humanist/patriot. [1] [37]
1489
- July 2
- Birth of Thomas Cranmer England, archbishop/reformer/martyr. [1]
1490
- February 17
- Birth of Charles de Bourbon officer/governor (Lombardy). [1]
- May 17
- Birth of Albert in Ansbach, Germany; last grand master of the Teutonic Knights, lord of East Prussia, founded the University of Königsberg in 1544. [1] [37]
- June 28
- Birth of Albrecht Margrave von Brandenburg; Cardinal, Elector of the Holy Roman Empire and Archbishop of Mainz. [1] [37]
1491
- June 28
- Birth of Henry VIII; King of England (1509-47). [1] [241.9]
1492
- January 12
- Birth of Andrea Alicati Italian author. [1]
- March 4
- Birth of Francesco de Layolle composer. [1]
- March 6
- Birth of Jean Luis Vives Spanish theory/humanist/reformer. [1]
- May 8
- Birth of Andreas Alciatus [Giovanni Andrea-Alciato], Italian lawyer. [1]
1493
- March 15
- Birth of Anne Pierre Adrien duke of Montmorency marshal of France. [1]
- May 1
- Birth of Phillippus Paracelsus Switzerland, physician/alchemist. [1]
- December 17
- Birth of Philippus A Paracelsus Swiss physician/alchemist (Liber paramixum). [1]
1494
- February 20
- Birth of Johan Friis chancellor (Denmark, helped establish Lutheranism). [1]
- March 1
- Birth of Il Bacchiacca [Franceso Ubertini] Italian painter. [1]
- March 24
- Birth of Georgius Agricola [Georg Bauer]]; German mineralogist (De Re Metallica). [1] [37]
- April 20
- Birth of John Agricola [Schneider] German theologist/prime minister. [1]
- May 25
- Birth of Jacopo Pontormo II Italy, painter (Sepulture of Christ). [1]
1495
- March 6
- Birth of Luigi Alamanni Italian poet (Opere Toscane, La Coltivazione). [1]
- March 8
- Birth of Juan de Dios Portugal/Spain, saint/founder (Brothers of Mercy). [1]
- March 25
- Birth of Leonhard Paminger composer. [1]
- November 21
- Birth of John Bale England, bishop/anti-catholic playwright (Kynge Johan). [1]
1497
- February 15
- Birth of Philipp Melanchthon Germany, Protestant reformer. [1]
- February 16
- Birth of Philipp Melanchthon Germany, Protestant reformer (Augsburgse Confessie). [1]
1498
- December 19
- Birth of Andreas Osiander Germany, Protestant Reformation theologist. [1]
1499
- March 31
- Birth of Pius IV [Gianangelo de' Medici], Italian lawyer/pope (1559-65). [1]
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