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What is Pippali rasayana?

Agarwal AK Singh M Gupta N Saxena R Puri A Verma AK Saxena RP

Dubey CB Saxena KC

Management of giardiasis by an immuno-modulatory herbal drug Pippali

rasayana.

[Additional information: ABSTRACT ONLINE, ADDRESS]

In: J Ethnopharmacol (1994 Dec) 44(3):143-6

<Adjuvants, Immunologic> <Drugs, Chinese Herbal> <Giardiasis>

<Administration, Oral> <Animal> <Giardia lamblia> <Hemagglutination>

Pippali rasayana (PR), an Ayurvedic herbal medicine, prepared from

Piper longum (Pippali) and Butea monosperma (Palash), and prescribed

for the treatment of chronic dysentery and worm infestations was

tested for anti-giardial and immuno-stimulatory activity in mice,

infected with Giardia lamblia trophozoites. It produced up to 98%

recovery from the infection. The rasayana had no killing effect on

the parasite in vitro. It induced significant activation of

macrophages as evidenced by increased macrophage migration index

(MMI) and phagocytic activity. Enhancement of host resistance could

be one of the possible mechanisms contributing towards the recovery

of animals from the giardial infection.

Division of Biochemistry and Microbiology

Central Drug Research Institute

Lucknow

India.

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